Individualized IMRT treatment approach for cervical lymph node metastases of unknown primary

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Cervical lymph node metastases of squamous cell carcinoma from an unknown primary.

Cervical lymph node metastases of squamous cell carcinoma from occult primary constitute about 2-5% of all patients with carcinoma of unknown primary site (CUP). Metastases in the upper and middle neck are generally attributed to head and neck cancers, whereas the lower neck (supraclavicular area) involvement is often associated with primary malignancies below the clavicles. The diagnostic proc...

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Radiotherapeutic management of cervical lymph node metastases from an unknown primary site.

OBJECTIVE To determine whether ipsilateral radiotherapy affects overall survival, cause-specific survival, or local control in patients with a cancer from an unknown primary of the head and neck compared with comprehensive radiotherapy. DESIGN Retrospective medical record review. SETTING Academic tertiary care hospital. PATIENTS The study population comprised 46 patients with cervical met...

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Diagnostic and treatment modalities for patients with cervical lymph node metastases of unknown primary site – current status and challenges

BACKGROUND AND PURPOSE This review aims to provide a comprehensive overview of the literature and elucidate open questions for future clinical trials concerning diagnostics and treatment modalities for cervical cancer of unknown primary (CUP). METHODS A literature search for head and neck CUP was performed with focus on diagnostics and therapies as well as molecular markers. RESULTS High le...

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Surgical Treatment for Mediastinal Lymph Node Carcinoma of Unknown Primary

Carcinoma of unknown primary (CUP) is occasionally encountered in clinical oncology. Wide variation exists in CUP. We herein report a rare case of CUP of a mediastinal lymph node. A 61-year-old man with dermatomyositis was referred to our hospital for treatment of mediastinal adenopathy and gastric cancer. Biopsy of both lesions showed that they were histologically different from each other. Me...

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Impact of FDG-PET/CT for the Detection of Unknown Primary Tumours in Patients with Cervical Lymph Node Metastases

OBJECTIVE Because the detection of the primary tumour is of importance to optimize the patient's management and allows a targeted therapy, the performance of hybrid positron emission tomography-computed tomography (PET/CT) using fluorodeoxyglucose (FDG) in the detection of primary tumors and unrecognized metastases with cervical lymph node metastases were evaluated in a retrospective study. M...

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ژورنال

عنوان ژورنال: Strahlentherapie und Onkologie

سال: 2014

ISSN: 0179-7158,1439-099X

DOI: 10.1007/s00066-013-0508-x